Follicular Lymphoma Surveillance Imaging
Published: 2019-07-17 |
Author: Christina Bennett, MS |
Source: Cancer Therapy Advisor
A retrospective cohort study found that surveillance imaging for patients with follicular lymphoma (FL) did not improve their survival outcomes after first relapse, aligning with the results of a prior study that also showed a lack of association between surveillance imaging and overall survival improvement. The latest findings were reported at the 2019 American Society of Clinical Oncology (ASCO) Annual Meeting.
The study cohort population was composed of 117 patients who were retrospectively identified from a prospective study of 1121 newly diagnosed patients with FL who were enrolled in the University of Iowa/Mayo Clinic SPORE Molecular Epidemiology Resource (MER). The retrospectively identified patients had relapsed more that 26 weeks after induction therapy, and these relapsed patients included 59 who achieved a complete response, 51 who achieved a partial response, 6 who achieved stable disease, and 1 who achieved an unspecified response.
The median time to first relapse was 2.2 years and relapse could be detected either via clinical suspicion was the more frequent detection method, with 63 relapses detected via clinical suspicion and 50 relapses detected via surveillance imaging; 4 relapses had unknown detection method.